How Wegovy Works: Benefits, Dosing, and What to Expect
How Wegovy Works: Benefits, Dosing, and What to Expect

Introduction
Wegovy (semaglutide 2.4 mg) is one of the most effective FDA-approved medications for weight loss on the market today. It’s helped thousands of people lose significant weight without surgery and has become a go-to prescription for healthcare providers treating obesity.
In this guide, you’ll learn exactly how Wegovy works, what kind of results to expect, how the dosing schedule works, and what to know about side effects and safety.
What Is Wegovy?
Wegovy is a GLP-1 receptor agonist, which means it mimics a natural hormone called glucagon-like peptide-1. This hormone affects parts of your brain that control appetite and digestion.
Wegovy helps you lose weight by:
- Reducing appetite and cravings
- Slowing how quickly food leaves your stomach (so you feel fuller longer)
- Helping regulate blood sugar and insulin levels
Who Is Wegovy For?
Wegovy is FDA-approved for:
- Adults with a BMI ≥30 (obese), or
- Adults with a BMI ≥27 who also have a weight-related condition (such as high blood pressure, diabetes, or sleep apnea)
💡 It is not approved for cosmetic weight loss or short-term use.
Wegovy Weight Loss Results
Wegovy has shown impressive results in clinical trials and real-world use:
Timeframe | Expected Results |
First 4–8 weeks | Reduced appetite, some weight loss |
3–6 months | 10–15% total body weight lost |
12 months | Up to 16%+ weight loss for many patients |
📚 Source: STEP-1 Clinical Trial
Many patients lose 15–30 pounds or more, depending on their starting weight and consistency.
Wegovy Dosing Schedule
Wegovy uses a step-up dosing approach to reduce side effects and allow your body to adjust:
Week | Dose |
Weeks 1–4 | 0.25 mg/week |
Weeks 5–8 | 0.5 mg/week |
Weeks 9–12 | 1.0 mg/week |
Weeks 13–16 | 1.7 mg/week |
Week 17+ | 2.4 mg/week (maintenance dose) |
💡 Most people stay on the full 2.4 mg dose long-term, as long as it’s well-tolerated and effective.
Common Side Effects
Like other GLP-1 medications, Wegovy can cause digestive symptoms, especially during the first few weeks.
Common Side Effects | Serious (Rare) Side Effects |
Nausea | Pancreatitis |
Diarrhea or constipation | Gallbladder problems |
Fatigue or headache | Kidney issues |
Decreased appetite | Thyroid tumor risk (animal data) |
✅ Most side effects improve over time, especially when the dose is increased slowly.
📌 People with a personal or family history of MEN-2 or medullary thyroid cancer should avoid Wegovy.
How Wegovy Compares to Other Weight Loss Medications
Medication | Average Weight Loss | Dosing | FDA-Approved for Obesity |
Wegovy | 15%+ | Weekly | ✅ Yes |
Zepbound | Up to 22.5% | Weekly | ✅ Yes (2023) |
Saxenda | 5–8% | Daily | ✅ Yes |
Contrave | 5–10% | Daily pill | ✅ Yes |
How Much Does Wegovy Cost?
Source | Monthly Cost |
U.S. Retail Price | ~$1,349 |
Canadian Pharmacy | ~$500–$600 |
With Savings Card | As low as $0–$25 (for eligible patients) |
📌 Apply for the Wegovy Savings Card if you have commercial insurance. It can drastically reduce out-of-pocket costs.
FAQs About Wegovy
How soon will I see results?
Most patients notice reduced hunger in the first 1–2 weeks. Significant weight loss typically occurs after 8–12 weeks.
Do I need to diet and exercise too?
Yes. Wegovy is most effective when combined with healthy eating and regular activity.
What happens if I stop taking it?
Weight regain is likely without ongoing lifestyle changes. Some patients stay on Wegovy long-term under medical guidance.
Is it the same as Ozempic?
They share the same active ingredient (semaglutide), but Wegovy is specifically approved and dosed for weight loss.
Final Thoughts
Wegovy is one of the most effective FDA-approved medications for weight loss, helping patients lose 15% or more of their body weight over time. With a once-weekly dose and proven results, it’s a game-changer for those who qualify.
✔️ Backed by science
✔️ Easy-to-use pen injector
✔️ Safe for long-term use under supervision
✔️ Significant weight loss and metabolic benefits
📌 To check pricing, insurance coverage, and eligibility, visit our Wegovy Resource Center.