Introduction

Qsymia is an FDA-approved prescription weight loss medication that combines two existing drugs—phentermine and topiramate—into one daily capsule. This dual-action formula works by suppressing appetite and reducing food cravings, making it a popular option for individuals seeking non-GLP-1 alternatives to medications like Wegovy or Mounjaro.

What Is Qsymia?

Qsymia includes:

• Phentermine – a stimulant similar to an amphetamine that decreases appetite
• Topiramate – a seizure and migraine medication that helps reduce cravings and promote satiety

Together, they affect both hunger and reward pathways, supporting consistent weight loss when combined with diet and exercise.

FDA Approval & Indications

Use	Status
Chronic weight management	✅ FDA Approved

Approved for adults with:

• BMI ≥30, or
• BMI ≥27 with at least one weight-related condition (e.g., high blood pressure, diabetes, or high cholesterol)

 

How Effective Is Qsymia?

Qsymia has been shown to produce meaningful and sustained weight loss, especially when taken long-term and combined with lifestyle interventions.

• Average weight loss: 10–15% of body weight
• Some studies show up to 19% reduction with the highest dose
• Early response (≥3% weight loss in 12 weeks) is predictive of long-term success

📚 Source: CONQUER Clinical Trial – Qsymia Prescribing Information

Benefits of Qsymia

 ✅ Non-GLP-1 oral alternative
 ✅ One capsule per day
 ✅ Addresses both physical hunger and emotional cravings
 ✅ Affordable compared to newer weight loss drugs

Cost Comparison

Pharmacy	Monthly Cost
U.S. Retail	~$200–$250
Through Qsymia.com	~$98/month (with coupon)
Canadian Pharmacy	~Rarely available

💡 Many patients can access Qsymia through manufacturer programs or telehealth providers at a discounted flat rate.

Common Side Effects

Common	Less Common / Serious
Dry mouth	Mood or sleep disturbances
Tingling in hands/feet	Increased heart rate
Constipation	Eye problems (rare)
Dizziness	Cognitive “fog” or memory issues

⚠️ Qsymia is not safe during pregnancy due to a known risk of birth defects. Women of childbearing age should use effective contraception while on Qsymia.

Who Should Consider Qsymia?

✅ Ideal for:

• Adults looking for a non-injectable alternative
• Those with a history of overeating or compulsive food behavior
• Individuals who did not respond well to GLP-1s
• Patients needing a cost-effective oral option

❌ Not ideal for:

• People with cardiovascular disease or arrhythmias
• Individuals with glaucoma, hyperthyroidism, or a history of kidney stones
• Women who are pregnant or planning pregnancy

How to Save on Qsymia

1. Qsymia Advantage Program
   – Offers $98/month pricing for eligible patients
   – Requires enrollment through the official Qsymia pharmacy network
2. Prescription Discount Cards
   – Use GoodRx to compare local pharmacy pricing
3. Telehealth Access
   – Many platforms offer online consultations and prescription delivery for Qsymia

Frequently Asked Questions

How long can I take Qsymia?
 Qsymia is approved for long-term use if it remains effective and well-tolerated. Most patients stay on it for 12 months or longer.

Will Qsymia interact with other medications?
 It can. Inform your provider about all medications, especially those for mood, sleep, seizures, or heart conditions.

How soon will I see results?
 Weight loss often begins within 4–6 weeks. Patients who lose ≥3% of their body weight in the first 12 weeks are more likely to succeed long-term.

Is it a controlled substance?
 Yes. Phentermine is a Schedule IV controlled substance, so Qsymia is regulated and may not be refillable in bulk.

Final Thoughts

Qsymia offers a well-established, non-hormonal weight loss option for adults seeking significant results without injections. While not as trendy as newer medications, it remains clinically effective, especially for patients looking to address both appetite and cravings in one daily capsule.

✔️ Backed by years of data
 ✔️ FDA-approved since 2012
 ✔️ Lower cost than GLP-1 alternatives

📌 To explore cost-saving options and availability, visit our Qsymia pricing page.